Msh6GS/- cells (Figure S2B).DiscussionHere we show that our previously described strategy for the functional characterization of MSH2 VUS is often adaptedto classify missense mutations found inside the MSH6 gene of…
Product Name : m-PEG3-S-PEG4-propargylCAS : 2055040-85-0Formula : C18H34O7SMW: 394.5Description : m-PEG3-S-PEG4-propargyl is a PEG linker containing a propargyl group. The propargyl groups can react with azide-bearing compounds or biomolecules via…
Product Name : Aminooxy-PEG1-propargyl HCl saltCAS : 1895922-69-6Formula : C5H9NO2MW: 115.1Description : Methyltetrazine-PEG1-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be…
Product Name : t-Boc-aminooxy-PEG1-propargylCAS : 1895922-72-1Formula : C10H17NO4MW: 215.3Description : t-Boc-aminooxy-PEG1-propargyl is a click chemistry PEG linker with a t-Boc-aminooxy group. Price of 1-(2-Ethynylphenyl)ethanone The propargyl group can react with…
Product Name : Azido-PEG3-phosphonic acidCAS : 1964503-38-5Formula : C8H18N3O6PMW: 283.2Description : Azido-PEG3-phosphonic acid is a PEG linker containing an azide group and a phosphonic acid. The azide group enables Click…
Product Name : Propargyl-PEG2-TosCAS : 145916-41-2Formula : C12H14O4SMW: 254.3Description : Propargyl-PEG2-Tos is a PEG linker containing a tosyl group and a propargyl group. Fmoc-Lys(Me)2-OH (hydrochloride) web The hydrophilic PEG spacer…
Product Name : Sulfo DBCO-PEG4-amineCAS : 2055198-05-3Formula : C32H42N4O10SMW: 674.8Description : Sulfo DBCO-PEG4-Amine is a water-soluble carboxyl-reactive building block with extended PEG spacer arm. 2-Chloro-1,3,4-thiadiazole Chemical name In the presence…
Concern location biopsies, a hydrophobic solvent was used following the procedure previously described by our group (Franck et al., 2010; Longuespee et al., 2012a; van Remoortere et al., 2010). A…
Ilure at 7 years old Horseshoe kidneys Appropriate cataract Conductive hearing loss Cleft of 8th thoracic vertebra Alive SC5DL gene Heterozygote carriersYes (moderate severity)N/AUSG and MRI showed mild nonprogressive liver…
Product Name : Azido-PEG3-phosphonic acid ethyl esterCAS : 1337527-24-8Formula : C12H26N3O6PMW: 339.3Description : t-Boc-Aminooxy-PEG3-alcohol is a PEG3 derivative containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables…