Product Name :
PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-89]
Predicted band size :
98 kDa
Observed band size :
50-130 kDa
Synonyms:
Acure promyelocytic leukemia, inducer of antibody MYL antibody Pml antibody PML_HUMAN antibody PP8675 antibody Probable transcription factor PML antibody Promyelocytic leukemia antibody Promyelocytic leukemia inducer of antibody Promyelocytic leukemia protein antibody Protein PML antibody 展开
Function :
Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor protein required for the assembly of a number of nuclear structures, called PML-nuclear bodies, which form amongst the chromatin of the cell nucleus. These nuclear bodies are present in mammalian nuclei, at about 1 to 30 per cell nucleus. PML-NBs are known to have a number of regulatory cellular functions, including involvement in programmed cell death, genome stability, antiviral effects and controlling cell division. PML mutation or loss, and the subsequent dysregulation of these processes, has been implicated in a variety of cancers.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human PML Protein aa 1-600 / 882.(S)-3-Bromo-2-(1-methoxyethyl)pyridine web
Species reactivity:
Human
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
PSH02-89
RRID:
AB_3096672
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.(1-Phenylvinyl)boronic acid structure Aliquot store at -20℃.PMID:33619027 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 98 kDa
Positive control :
HeLa cell lysate, HEK-293 cell lysate, K-562 cell lysate, A549 cell lysate, MDA-MB-231 cell lysate, A431 cell lysate, human brain tissue, human breast carcinoma tissue, human breast tissue, human placenta tissue, human testis tissue, MDA-MB-231, A431.