Product Name :
TTK Rabbit Polyclonal Antibody
Predicted band size :
97 kDa
Observed band size :
Synonyms:
cancer/testis antigen 96 antibody CT96 antibody Dual specificity protein kinase TTK antibody ECSTY kinase antibody ESK antibody FLJ38280 antibody hMPS1 antibody Monopolar Spindle 1 Like 1 antibody MPH1 antibody Mps 1 antibody 展开
Function :
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human TTK aa 1-300.Price of Aminoethyl-SS-propionic acid
Species reactivity:
Human
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3071345
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.(R)-3-Fluoropyrrolidine (hydrochloride) structure Aliquot store at -20℃.PMID:33729077 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 97 kDa
Positive control :
Human placenta tissue lysates, human lung tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, SH-SY5Y, MG-63.