Product Name :
Smad2 Recombinant Rabbit Monoclonal Antibody [SP06-05]
Predicted band size :
52 kDa
Observed band size :
58 kDa
Synonyms:
Drosophila, homolog of, MADR2 antibody hMAD-2 antibody HsMAD2 antibody JV18 antibody JV18-1 antibody JV181 antibody MAD antibody MAD homolog 2 antibody MAD Related Protein 2 antibody Mad-related protein 2 antibody 展开
Function :
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human Smad2 aa 220-270.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, IP, FC
Coupling :
unconjugated
Clone number:
SP06-05
RRID:
AB_3069690
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol.2,2-Dibenzylpropane-1,3-diol Chemical name Preservative: 0.Formula of 78703-55-6 05% Sodium Azide.PMID:33654226
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 52 kDa
Positive control :
HeLa cell lysate, HT-29 cell lysate, Jurkat cell lysate, HL-60 cell lysate, C2C12 cell lysate, mouse lung tissue lysate, mouse placenta tissue lysate, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue, HepG2, NIH/3T3.