Product Name :
RBBP5 Rabbit Polyclonal Antibody
Predicted band size :
59 kDa
Observed band size :
59 kDa
Synonyms:
RBBP 5 antibody RBBP-5 antibody RBBP5 antibody RBBP5_HUMAN antibody RBQ 3 antibody RBQ3 antibody Retinoblastoma binding protein 5 antibody Retinoblastoma binding protein RBQ3 antibody Retinoblastoma binding protein5 antibody Retinoblastoma-binding protein 5 antibody 展开
Function :
In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 ‘Lys-4’ methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at ‘Lys-4’ of histone H3. Histone H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.501015-16-3 Order
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human RBBP5 aa 1-50.2-Amino-5-chloro-4-methoxybenzoic acid In stock
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3071474
Form :
Liquid
Concentration :
2.PMID:33618587 1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 59 kDa
Positive control :
293 cell lysate, MCF-7 cell lysate, human lung carcinoma tissue, human colon tissue.