Product Name :
PPP2R5C Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
2A5G_HUMAN antibody B’ alpha regulatory subunit antibody B56G antibody KIAA0044 antibody MGC23064 antibody PP2A B subunit B’ gamma isoform antibody PP2A B subunit B56 gamma isoform antibody PP2A B subunit isoform B’ gamma antibody PP2A B subunit isoform B”-gamma antibody PP2A B subunit isoform B56-gamma antibody 展开
Function :
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human PPP2R5C 390-435/524
Species reactivity:
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
Verify application:
WB, ELISA, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1175052-07-9 structure Avoid repeated freeze/thaw cycles.5-Bromo-4-chloro-2-methylpyrimidine Chemical name The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33635174 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
61 KDa
Positive control :
Highest levels in heart, skeletal muscle and brain. Lower levels in pancreas, kidney, lung and placenta. Very low levels in liver.