Rticles were then washed extensively with Dulbecco’s phosphate-buffered saline (DPBS, Invitrogen, Cat.No. 14190250) and re-suspended to get a concentrated 5 v/v stock option. The particles have been shown to become…
The disappearance of total JNK inside the mitochondria is quite comparable for the disappearance of p-JNK. It truly is not entirely clear if the dephosphorylation of JNK outcomes in loss…
Product Name : PEG5-MsCAS : 65883-12-7Formula : C9H20O7SMW: 272.3Description : PEG5-Ms is a PEG linker with a mesyl group and a hydroxyl group. Ethyl 2-formylthiazole-4-carboxylate Chemscene (4-Bromopyridin-2-yl)methanamine web The mesyl…
Product Name : Pyrene-PEG5-alcoholCAS : 1817735-44-6Formula : C27H31NO6MW: 465.6Description : DBCO-PEG-8-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit linkers can be cleaved by Cathepsin B. The DBCO groups is commonly…
Product Name : 1,1,1-Trifluoroethyl-PEG4-azideCAS : 1817735-35-5Formula : C10H18F3N3O4MW: 301.3Description : 1,1,1-Trifluoroethyl-PEG4-azide is a crosslinker containing an azide group and a trifluoroethyl group. The azide group enables Click Chemistry. The hydrophilic…
Product Name : 1,1,1-Trifluoroethyl-PEG5-PropargylCAS : 1817735-37-7Formula : C13H21F3O5MW: 314.3Description : 1,1,1-Trifluoroethyl-PEG5-Propargyl forms triazole linkage with azides via copper catalyzed azide-alkyne Click Chemistry. The trifluoroethyl group is reactive towards primary amine…
Product Name : Methylamino-PEG5-azideCAS : 2055046-24-5Formula : C13H28N4O5MW: 320.4Description : Methylamino-PEG5-azide is a PEG linker containing an azide group and a methylamino group. The azide group enables Click Chemistry. The…
Product Name : Tetra(Cyanoethoxymethyl) MethaneCAS : 2465-91-0Formula : C17H24N4O4MW: 348.4Description : Tetra(cyanoethoxymethyl) methane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. The nitrile…
Evealed that TBME and K2CO3 were optimal, providing tertiary alcohol 2b with 20:1 diastereoselection and 96:4 er (Table 1, entry 10). Efforts to further enhance stereoselectivity by introduction of steric…
He WT, whereas U5 snRNA cross-links to Prp8 at related levels in each strains. (f) Spliceosomal B complicated assembled in the U1 ?84?12 strain has comparable U1 snRNA level but…